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Acquisition of Zavante (Details) - Zavante Therapeutics
$ in Millions
Jul. 24, 2018
USD ($)
shares
Acquisition of Zavante  
Percentage of entity shares held by subsidiary 19.90%
Milestone payment receivable prior acquisition $ 3.0
Threshold milestone payment that may be settled in ordinary shares 26.0
In-process research and development expense 32.0
Transaction costs 4.8
Net liabilities assumed 0.2
Maximum  
Acquisition of Zavante  
Contingent consideration 97.5
Upfront Shares  
Acquisition of Zavante  
Expense from the fair value of shares issued in the acquisition $ 26.9
Upfront Shares  
Acquisition of Zavante  
Business acquisition, shares issued or issuable | shares 7,336,906
Holdback Shares  
Acquisition of Zavante  
Business acquisition, shares issued or issuable | shares 815,186
Approval Milestone Payment  
Acquisition of Zavante  
Contingent consideration $ 25.0
Net Sales Milestone Payments  
Acquisition of Zavante  
Contingent consideration $ 72.5