Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Revenues:
Total revenue	$ 9,481	$ 9,656	$ 5,319
Operating expenses:
Cost of product sales	(70)
Research and development expenses	(26,415)	(82,288)	(49,615)
Selling, general and administrative expenses	(62,485)	(41,743)	(29,472)
Total operating expenses	(88,970)	(124,031)	(79,087)
Loss from operations	(79,489)	(114,375)	(73,768)
Other income (expense):
Other income (expense), net	215	(272)	492
Interest income	255	49	318
Interest expense	(3,644)	(133)	(43)
Loss before income taxes	(82,663)	(114,731)	(73,001)
Income tax expense	(101)	(49)	(1,355)
Net loss	(82,764)	(114,780)	(74,356)
Other comprehensive income (loss), net of tax
Unrealized losses on available-for-sale securities			(26)
Reclassification to net income			(43)
Other comprehensive income, net of tax			17
Comprehensive loss	$ (82,764)	$ (114,780)	$ (74,339)
Loss per share
Basic and Diluted ($ per share)	$ (1.12)	$ (2.26)	$ (2.49)
Weighted average number of shares:
Basic and Diluted	74,199,482	50,795,768	29,830,669
Product revenue, net
Revenues:
Total revenue	$ 1,538
Collaboration revenue
Revenues:
Total revenue	6,210	$ 6,500
Research premium and grant revenue
Revenues:
Total revenue	$ 1,733	$ 3,156	$ 5,319