Condensed Consolidated Balance Sheets (unaudited) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 77,741	$ 95,529
Short-term investments	70,823	83,037
Prepaid expenses and other current assets	8,783	12,261
Total current assets	157,347	190,827
Property and equipment, net	4,406	4,882
Long-term investments	13,691	41,657
Operating lease right-of-use asset	10,271	11,877
Other non-current assets	3,186	3,453
Total assets	188,901	252,696
Current liabilities:
Accounts payable	3,439	1,674
Accrued expenses	15,801	13,467
Operating lease liability, current	3,912	3,695
Other current liabilities	43	62
Total current liabilities	23,195	18,898
Operating lease liability, net of current portion	7,976	9,993
Total liabilities	31,171	28,891
Commitments and contingencies
Stockholders’ equity:
Preferred stock, $0.001 par value: 5,000 shares authorized at June 30, 2022 and December 31, 2021; no shares issued or outstanding at June 30, 2022 or December 31, 2021	0	0
Common stock, $0.001 par value: 160,000 shares authorized at June 30, 2022 and December 31, 2021; 51,681 and 51,265 shares issued and outstanding at June 30, 2022 and December 31, 2021, respectively	51	51
Additional paid-in capital	471,529	465,865
Accumulated other comprehensive loss	(1,097)	(238)
Accumulated deficit	(312,753)	(241,873)
Total stockholders’ equity	157,730	223,805
Total liabilities and stockholders’ equity	$ 188,901	$ 252,696