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Property and Equipment, Net
 12 Months Ended
Dec. 31, 2018
Property, Plant and Equipment [Abstract]  
Property and Equipment, Net
Property and Equipment, Net
Property and equipment, net as of December 31, 2018 and 2017 was comprised as follows (in thousands):
 
Estimated Useful Life (in Years)
 
December 31,
 
 
2018
 
2017
Laboratory equipment
5
 
$
10,435

 
$
9,409

Furniture and office equipment
4
 
1,071

 
1,038

Computer equipment
3
 
1,505

 
1,380

Leasehold improvements
Shorter of useful life or remaining lease term
 
8,534

 
8,498

Total property and equipment, gross
 
 
21,545

 
20,325

Less: accumulated depreciation
 
 
(8,005
)
 
(4,174
)
Total property and equipment, net
 
 
$
13,540

 
$
16,151


Depreciation expense for the years ended December 31, 2018 and 2017 was $3.8 million and $4.4 million, respectively.