Significant Agreements - Litigation (Details) $ in Millions	12 Months Ended
	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2016 USD ($) multiple	Dec. 31, 2017 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Deductions	$ 0.0	$ 0.0	$ 40.0
Loss Contingency [Abstract]
Contingency reserves for litigation liabilities	$ 0.0	$ 0.0
Non-profit organization agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum funding				$ 4.0
Funding multiple | multiple				2.6
Milestone payment liability					$ 1.0