Significant Agreements - Neurocrine Collaboration Agreements (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended				9 Months Ended
	Sep. 30, 2024	Apr. 30, 2024	Sep. 30, 2024	Jun. 30, 2024	Mar. 31, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration revenue			$ 24,629			$ 4,614	$ 73,723	$ 159,947
2019 Neurocrine Collaborative Agreement | Neurocrine
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payments					$ 5,000
Allocation of transaction price					5,000
Cumulative catch up of revenue recognized					$ 4,400
2023 Neurocrine Collaborative Agreement | Neurocrine
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration revenue				$ 3,000
Milestone payments	$ 3,000	$ 3,000
Allocation of transaction price	$ 3,000		3,000				$ 3,000
Cumulative catch up of revenue recognized			$ 2,000