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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Cash flow from operating activities    
Net (loss) income $ (11,330) $ 124,044
Adjustments to reconcile net (loss) income to net cash provided by operating activities:    
Stock-based compensation expense 3,573 2,558
Depreciation 1,196 1,075
Amortization of premiums and discounts on marketable securities (1,931) (17)
Loss on disposal of fixed assets 59 44
Changes in operating assets and liabilities:    
Accounts receivable 79,313 (25,000)
Related party collaboration receivable 721 (71)
Prepaid expenses and other current assets (794) 1,411
Operating lease, right-of-use asset 1,057 469
Other non-current assets (15)  
Accounts payable 5,975 1,132
Accrued expenses (9,305) (122)
Operating lease liabilities 891 (683)
Deferred revenue (10,643) 18,725
Net cash provided by operating activities 58,767 123,565
Cash flow from investing activities    
Purchases of property and equipment (2,141) (509)
Purchases of marketable securities (203,852)  
Proceeds from sales and maturities of marketable securities 109,928 15,000
Net cash (used in) provided by investing activities (96,065) 14,491
Cash flow from financing activities    
Proceeds from the exercise of stock options 78 185
Proceeds from the issuance of common stock in connection with the underwritten public offering 93,473  
Proceeds from the issuance of common stock in connection with the 2023 Novartis Stock Purchase Agreement 19,305  
Proceeds from the issuance of common stock in connection with the 2023 Neurocrine Collaboration Agreement   31,121
Net cash provided by financing activities 112,856 31,306
Net increase in cash, cash equivalents, and restricted cash 75,558 169,362
Cash, cash equivalents, and restricted cash, beginning of period 70,395 100,474
Cash, cash equivalents, and restricted cash, end of period 145,953 269,836
Supplemental disclosure of cash and non-cash activities    
Capital expenditures incurred but not yet paid   $ 109
Operating lease right-of-use assets obtained in exchange for operating lease liabilities $ 26,751