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Related party transactions (Details) - USD ($)	3 Months Ended		9 Months Ended
Related party transactions (Details) - USD ($)	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Jun. 30, 2023	Dec. 31, 2022
Related party transactions
Related party collaboration receivable	$ 3,253,000		$ 3,253,000			$ 257,000
Dr. Sah \| Related Party
Related party transactions
Total amount of services received	157,500	$ 93,600	541,300	$ 185,925
Advisory fee amount per month					$ 50,000
Dr. Sandrock \| Related Party
Related party transactions
Total amount of services received				$ 60,000
Neurocrine
Related party transactions
Related party collaboration receivable	1,919,000		1,919,000
Neurocrine Collaborative Agreement 2019 \| Neurocrine \| Related Party
Related party transactions
Related party collaboration receivable	1,300,000		1,300,000
Neurocrine Collaborative Agreement 2023 \| Neurocrine \| Related Party
Related party transactions
Related party collaboration receivable	$ 1,900,000		$ 1,900,000