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Significant agreements - Collaboration receivables and contract liabilities (Details)
$ in Thousands
9 Months Ended
Sep. 30, 2023
USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]  
Related party collaboration receivables, beginning balance $ 257
Related party collaboration receivables, ending balance 3,253
Neurocrine  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]  
Additions 4,364
Deductions (2,445)
Related party collaboration receivables, ending balance 1,919
Additions 74,420
Deductions (1,643)
Deferred revenue, ending balance $ 72,777