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Related party transactions (Details) - USD ($)	3 Months Ended		6 Months Ended
Related party transactions (Details) - USD ($)	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
Related party transactions
Related party collaboration receivable	$ 3,350,000		$ 3,350,000		$ 257,000
Dr. Sah \| Related Party
Related party transactions
Total amount of services received	184,000	$ 82,425	383,800	$ 92,325
Advisory fee amount per month	50,000		50,000
Dr. Sandrock \| Related Party
Related party transactions
Total amount of services received				$ 60,000
Neurocrine
Related party transactions
Related party collaboration receivable	2,239,000		2,239,000
Neurocrine Collaborative Agreement 2019 \| Neurocrine \| Related Party
Related party transactions
Related party collaboration receivable	800,000		800,000
Neurocrine Collaborative Agreement 2023 \| Neurocrine \| Related Party
Related party transactions
Related party collaboration receivable	$ 2,200,000		$ 2,200,000