Commitments and contingencies (Tables)

6 Months Ended

Jun. 30, 2023

Schedule of collaboration receivables and contract liabilities

	Balance at						Balance at
	December 31, 2022		Additions		Deductions		June 30, 2023
		(in thousands)
Related party collaboration receivable	$	-		2,239	$	-	$	2,239
Contract liabilities:
Deferred revenue	$	-		74,420	$	(689)	$	73,731

Neurocrine Collaboration Agreement

Schedule of allocation of variable consideration

Performance Obligation	Amount
	(in thousands)
Variable Consideration
GBA1 Program	$	5,361
2023 Discovery Program 1		166
2023 Discovery Program 2		166
2023 Discovery Program 3		166
Total	$	5,859

Schedule of allocation of fixed consideration

Performance Obligation	Amount
	(in thousands)
Fixed Consideration
GBA1 Program	$	69,459
2023 Discovery Program 1		24,807
2023 Discovery Program 2		24,807
2023 Discovery Program 3		24,807
Total	$	143,880