Consolidated Statements of Operations and Comprehensive (Loss) Income - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Consolidated Statements of Operations and Comprehensive (Loss) Income
Collaboration revenue	$ 40,907	$ 37,415	$ 171,128
Operating expenses:
Research and development	60,764	73,787	108,753
General and administrative	30,980	37,246	34,991
Total operating expenses	91,744	111,033	143,744
Operating (loss) income	(50,837)	(73,618)	27,384
Other income, net:
Interest income (expense)	1,792	(390)	1,659
Other income	2,653	2,811	7,698
Total other income, net	4,445	2,421	9,357
(Loss) income before income taxes	(46,392)	(71,197)	36,741
Income tax provision	16
Net (loss) income	(46,408)	(71,197)	36,741
Other comprehensive (loss) income
Net unrealized loss on available-for-sale-securities	(81)	(4)	(30)
Total other comprehensive loss	(81)	(4)	(30)
Comprehensive (loss) income	$ (46,489)	$ (71,201)	$ 36,711
Net (loss) income per share, basic	$ (1.21)	$ (1.89)	$ 0.99
Net (loss) income per share, diluted	$ (1.21)	$ (1.89)	$ 0.98
Weighted-average common shares outstanding, basic	38,356,810	37,668,947	37,132,447
Weighted-average common shares outstanding, diluted	38,356,810	37,668,947	37,348,514