Commitments and contingencies (Tables)

12 Months Ended

Dec. 31, 2022

Schedule of collaboration receivables and contract liabilities

	Balance at						Balance at
	December 31, 2021		Additions		Deductions		December 31, 2022
		(in thousands)
Related party collaboration receivable	$	732	$	907	$	(1,382)	$	257
Contract liabilities:
Deferred revenue	$	12,096	$	—	$	(269)	$	11,827

Neurocrine Collaboration Agreement

Schedule of allocation of variable consideration

Performance Obligation	Amount
	(in thousands)
Variable Consideration
VY-AADC Program	$	53,863
FA Program		18,868
2019 Discovery Program 1		5,336
2019 Discovery Program 2		3,605
Total	$	81,671

Schedule of allocation of fixed consideration

Performance Obligation	Amount
	(in thousands)
Fixed Consideration
VY-AADC Program	$	49,045
FA Program		20,647
2019 Discovery Program 1		14,443
2019 Discovery Program 2		8,247
Total	$	92,382