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Prepaid expenses and other current assets (Details) - USD ($)
$ in Thousands
Dec. 31, 2018
Dec. 31, 2017
Prepaid expense and other current assets    
Prepaid research and development contracts $ 4,497 $ 1,330
Other current assets 1,360 766
Prepaid insurance 617 520
Accrued interest receivable 201 122
Total $ 6,675 $ 2,738