X0306 4 2017-05-11 0 0001232524 Jazz Pharmaceuticals plc JAZZ 0001639637 Smith Karen L. 5TH FL, WATERLOO EXCHANGE WATERLOO RD DUBLIN 4 L2 IRELAND 0 1 0 0 EVP, R&D and CMO Ordinary Shares 2017-05-11 4 F 0 641 155.18 D 20527 D Ordinary Shares 2017-05-11 4 A 0 1000 0.0 A 21527 D Non-Qualified Stock Option (right to buy) 155.18 2017-05-11 4 A 0 2500 0.0 A 2027-05-10 Ordinary Shares 2500 2500 D Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units. These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of June 5, 2017, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years. These options are granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the grant date, May 11, 2017, with 1/4th vesting on the first anniversary of the grant date and the remainder vesting in 36 equal monthly installments thereafter. By: /s/ Peter A Christou as attorney in fact For: Karen Lesley Smith 2017-05-12