X0306 4 2017-06-19 0 0001626878 XBiotech Inc. XBIT 0001639078 SIMARD JOHN 8201 EAST RIVERSIDE DRIVE BUILDING 4, SUITE 100 AUSTIN TX 78744 1 1 1 0 Chief Executive Officer Stock Option 4.24 2017-06-19 4 M 0 75000 4.24 A 2018-06-19 2027-06-19 Common Stock 50000 75000 D On September 14, 2016 (the Grant Date) Fabrizio Bonanni was granted nonstatutory stock options (the Options) under the Company's 2015 Equity Incentive Plan to purcahse shares of the Company's Common Stock (the Shares) at an exercise price equal to the closing sales price of the Shares on the Grant Date as quoted by the Nasdaq Stock Market, with an expiry of ten years from the Grant Date. Half of the Options vest on December 20, 2016 and another half of the Options vest on June 20, 2017. On June 19, 2017 (the Grant Date) the reporting person was granted nonstatutory stock options (the Options) under the Company's 2015 Equity Incentive Plan to purchase shares of the Company's Common Stock (the Shares) at an exercise price equal to the closing sales price of the Shares on the Grant Date as quoted by the Nasdaq Stock Market. The Options vest in three equal annual installments commencing as of the first anniversary of the Grant Date with an expiry of ten years from the Grant Date. /s/ Ashley Otero under Power of Attorney for John Simard 2017-06-23