X0306 4 2015-04-21 0 0001434647 KEMPHARM, INC KMPH 0001638366 Mickle Christal M M C/O KEMPHARM, INC. 2656 CROSSPARK ROAD, SUITE 100 CORALVILLE IA 52241 0 1 1 0 VP Operations & Prod Dev Common Stock 2015-04-21 4 C 0 5983 A 277094 D Common Stock 1538373 I By Spouse Common Stock 2015-04-21 4 C 0 96288 A 96288 D Common Stock 230812 I By Travis C Mickle & Christal M.M. Mickle TRS UA 4-30-09 Common Stock 230812 I By Travis C Mickle & Christal M.M. Mickle TRS UA 4-30-09 Series A Convertible Preferred Stock 2015-04-21 4 C 0 527093 0.00 D Common Stock 70279 0 D Series B Convertible Preferred Stock 2015-04-21 4 C 0 6203 0.00 D Common Stock 827 0 D Series C Convertible Preferred Stock 2015-04-21 4 C 0 51332 0.00 D Common Stock 6844 0 D Series C Convertible Preferred Stock 2015-04-21 4 C 0 44873 0.00 D Common Stock 5983 0 D Series D Convertible Preferred Stock 2015-04-21 4 C 0 137541 0.00 D Common Stock 18338 0 D Warrant to Purchase Series D Preferred Stock (right to buy) 2015-04-21 4 C 0 32371 0.78 D Common Stock 4316 0 D Warrant to Purchase Common Stock (right to buy) 5.85 2015-04-21 4 C 0 4316 0.00 D Common Stock 4316 4316 D The total represents shares received upon conversion of Series A, Series B, Series C and Series D convertible preferred stock. Effective upon the closing of the Issuer's initial public offering of its common stock, each share of Series A, Series B, Series C and Series D convertible preferred stock automatically converted into 0.133333 shares of common stock. The convertible preferred stock had no expiration date. Held jointly with spouse. Represents a warrant to purchase shares of common stock of the Issuer following the conversion of the Series D convertible preferred stock on a 1-for-0.1333 share basis. The number of shares and price per share reported herein reflects such conversion. The warrant is immediately exercisable at any time at the option of the holder. The warrant expires as of 5:00 p.m. C.S.T. on the earliest of (i) June 2, 2019 and (ii) the effective date of the closing of a Company Sale Transaction (as such term is defined in the warrant). /s/ James C.T. Linfield, Attorney-in-Fact 2015-04-21