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Stock-Based Compensation - Stock Options (Details) - $ / shares
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
May 11, 2022
Stock Options, Additional Disclosures            
Stock options outstanding 36,493   36,493   32,498  
Outstanding, Number, Beginning Balance (in shares)     32,498      
Granted (in shares)     5,995      
Forfeited/Cancelled (in shares)     (2,000)      
Outstanding, Number, Ending Balance (in shares) 36,493   36,493   32,498  
Vested and expected to vest (in shares) 36,493   36,493      
Options Exercisable (in share) 8,236   8,236      
Outstanding, Weighted Average Exercise Price, Beginning Balance (in dollars per share)     $ 119.72      
Granted (in dollars per share)     17.83      
Forfeited/Cancelled (in dollars per share)     181.20      
Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share) $ 99.62   99.62   $ 119.72  
Vested and expected to vest (in dollars per share) 99.62   99.62      
Options Exercisable (in dollars per share) $ 234.37   $ 234.37      
Options, Outstanding, Weighted Average Remaining Contractual Term (years)     8 years 9 months 18 days   9 years 3 months 18 days  
Vested and expected to vest (years)     8 years 9 months 18 days      
Options Exercisable (years)     7 years 6 months      
2018 Plan            
Stock Options, Additional Disclosures            
Stock options outstanding           0
Stock options | Employees, Directors And Consultants            
Stock Options, Additional Disclosures            
Granted (in shares) 0          
Stock options | Non Employee Director            
Stock Options, Additional Disclosures            
Vesting period   3 years   3 years    
Granted (in shares)   2,000 5,995 2,000    
Weighted average fair value per share of options granted   $ 90.35 $ 12.43 $ 90.35    
Minimum | Stock options | Non Employee Director            
Stock Options, Additional Disclosures            
Vesting period     1 year      
Maximum | Stock options | 2019 Plan            
Stock Options, Additional Disclosures            
Expiration period     10 years      
Maximum | Stock options | Non Employee Director            
Stock Options, Additional Disclosures            
Vesting period     3 years