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Income Taxes - Reconciliation of income tax (Details)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Reconciliation of income tax:    
Income tax (benefit) provision at federal statutory rate (as a percent) 21.00% 21.00%
State income tax, net of federal benefit (as a percent) 6.30% 6.30%
Acquired in-process research and development expense (15.60%)  
Valuation allowance (10.40%) (27.90%)
Convertible notes (as a percent) (1.60%)  
Research credits (as a percent) 0.80% 1.00%
Other (as a percent) (0.50%) (0.40%)