Commitments and Contingencies -Pfz (Details) - USD ($)	1 Months Ended	12 Months Ended
	Mar. 31, 2015	Dec. 31, 2019
License Agreements
Milestones or royalty payments triggered		$ 0
Pfizer, Inc. | License Agreement
License Agreements
Number of years after the first commercial sale	P5Y
Notice period	90 days
Pfizer, Inc. | License Agreement | Milestone Payments | Maximum | Pfizer, Inc.
License Agreements
Potential payments upon achievement of certain milestones	$ 37,000,000