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Condensed Statements of Changes in Stockholders’ Equity (Deficit) - USD ($)
Common Stock
Private placement
Common Stock
Additional Paid-in Capital
Private placement
Additional Paid-in Capital
Accumulated Deficit
Private placement
Total
Balance at beginning of period at Dec. 31, 2015   $ 12,000     $ (12,392,000)   $ (12,380,000)
Balance at beginning of period (shares) at Dec. 31, 2015   3,758,488          
Increase (Decrease) in Stockholders' Equity              
Redemption value adjustment - Series A preferred stock       $ (285,000) (81,000)   (366,000)
Conversion of Series A preferred stock to common stock   $ 1,000   8,318,000     8,319,000
Conversion of Series A preferred stock to common stock (in shares)   827,205          
Separation of convertible note beneficial conversion feature upon contingency resolution       372,000     372,000
Conversion of convertible notes to common stock   $ 1,000   11,444,000     11,445,000
Conversion of convertible notes to common stock (in shares)   1,656,807          
Issuance of common stock from offering   $ 3,000   30,275,000     30,278,000
Issuance of common stock from offering (in shares)   3,027,755          
Issuance costs of offering       (4,168,000)     (4,168,000)
Share-based compensation - employee       1,498,000     1,498,000
Share-based compensation - non-employee       220,000     220,000
Net loss         (14,586,000)   (14,586,000)
Balance at end of period at Dec. 31, 2016   $ 17,000   47,674,000 (27,059,000)   20,632,000
Balance at end of period (shares) at Dec. 31, 2016   9,270,255          
Increase (Decrease) in Stockholders' Equity              
Issuance of common stock from offering $ 1,000   $ 8,978,000     $ 8,979,000  
Issuance of common stock from offering (in shares) 1,324,256            
Issuance costs of offering     (1,287,000)     (1,287,000)  
Exercise of stock options       41,000     41,000
Exercise of stock options (in shares)   23,531          
Issuance of detachable stock warrants in connection with private placement     $ 3,562,000     $ 3,562,000  
Exercise of warrants       156,000     $ 156,000
Exercise of warrants (in shares)   15,000         15,000
Share-based compensation - employee       5,244,000     $ 5,244,000
Share-based compensation - non-employee       29,000     29,000
Net loss         (33,415,000)   (33,415,000)
Balance at end of period at Dec. 31, 2017   $ 18,000   64,397,000 (60,474,000)   3,941,000
Balance at end of period (shares) at Dec. 31, 2017   10,633,042          
Increase (Decrease) in Stockholders' Equity              
Issuance of common stock from offering   $ 4,000   25,146,000     25,150,000
Issuance of common stock from offering (in shares)   3,592,858          
Issuance costs of offering       (2,091,000)     (2,091,000)
Warrant issuance       196,000     196,000
Exercise of stock options       84,000     84,000
Exercise of stock options (in shares)   39,511          
Exercise of warrants             0
Share-based compensation - employee       4,128,000     4,128,000
Share-based compensation - non-employee       3,000     3,000
Net loss         (23,637,000)   (23,637,000)
Balance at end of period at Dec. 31, 2018   $ 22,000   $ 91,863,000 $ (84,111,000)   $ 7,774,000
Balance at end of period (shares) at Dec. 31, 2018   14,265,411