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Condensed Statements of Comprehensive Loss - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Operating expenses:                      
General and administrative $ 1,468,000 $ 2,364,000 $ 2,574,000 $ 2,087,000 $ 1,487,000 $ 2,050,000 $ 4,678,000 $ 2,223,000 $ 8,493,000 $ 10,438,000 $ 5,956,000
Research and development 1,833,000 3,542,000 3,960,000 4,977,000 5,080,000 6,489,000 5,837,000 5,280,000 14,312,000 22,686,000 8,740,000
Total operating expenses 3,301,000 5,906,000 6,534,000 7,064,000 6,567,000 8,539,000 10,515,000 7,503,000 22,805,000 33,124,000 14,696,000
Loss from operations (3,301,000) (5,906,000) (6,534,000) (7,064,000) (6,567,000) (8,539,000) (10,515,000) (7,503,000) (22,805,000) (33,124,000) (14,696,000)
Interest (expense) income (178,000) (172,000) (144,000) (160,000) (179,000) (132,000) 13,000 12,000 (654,000) (286,000) 114,000
Other expense (177,000) (1,000)           (5,000) (178,000) (5,000) (4,000)
Loss before income taxes (3,656,000) (6,079,000) (6,678,000) (7,224,000) (6,746,000) (8,671,000) (10,502,000) (7,496,000) (23,637,000) (33,415,000) (14,586,000)
Provision (benefit) for income taxes                 0    
Net loss (3,656,000) (6,079,000) (6,678,000) (7,224,000) (6,746,000) (8,671,000) (10,502,000) (7,496,000) (23,637,000) (33,415,000) (14,586,000)
Comprehensive loss $ (3,656,000) $ (6,079,000) $ (6,678,000) $ (7,224,000) (6,746,000) (8,671,000) (10,502,000) (7,496,000) (23,637,000) (33,415,000) (14,586,000)
Adjustment to redemption value on Series A convertible preferred stock         $ (0.63) $ (0.82) $ (0.99) $ (0.79)     (366,000)
Net loss attributable to common stockholders                 $ (23,637,000) $ (33,415,000) $ (14,952,000)
Net loss per share:                      
Basic and diluted (Note 10) $ (0.26) $ (0.43) $ (0.47) $ (0.58)         $ (1.71) $ (3.23) $ (2.57)
Number of shares used in per share calculations:                      
Basic and diluted                 13,805,552 10,349,136 5,809,396