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Commitments and Contigencies - Pfizer License Agreement (Details) - USD ($)
$ in Thousands
Mar. 31, 2017
Dec. 31, 2016
Commitments and Contingencies    
No liabilities were recorded related to the license agreement $ 4,545 $ 4,122
Pfizer, Inc. | License Agreement    
Commitments and Contingencies    
No liabilities were recorded related to the license agreement $ 0