July 8, 2025

Hyung Heon Kim
Chief Executive Officer
MetaVia Inc.
545 Concord Avenue, Suite 210
Cambridge, MA 02138

       Re: MetaVia Inc.
           Registration Statement on Form S-3
           Filed July 2, 2025
           File No. 333-288486
Dear Hyung Heon Kim:

       This is to advise you that we have not reviewed and will not review your
registration
statement.

        Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you
that the company and its management are responsible for the accuracy and
adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.

       Please contact Tyler Howes at 202-551-3370 with any questions.



                                                           Sincerely,

                                                           Division of
Corporation Finance
                                                           Office of Life
Sciences
cc:   Josh Damm, Esq.