SCHEDULE 13G 0000944809 XXXXXXXX LIVE Ordinary Shares Nominal value of NIS 0.0000769 per share 03/16/2025 0001638097 Entera Bio Ltd. M40527109 KIRYAT HADASSAH, MINRAV BUILDING FIFTH FLOOR JERUSALEM L3 9112002 Rule 13d-1(c) OPKO HEALTH, INC. DE 3685226.00 0.00 3685226.00 0.00 3685226.00 8.1 CO Based on 45,420,676 shares of ordinary shares of the Issuer outstanding on March 20, 2025, as set forth in the Issuer's Form 10-K filed with the Securities and Exchange Commission (the "SEC") on March 28, 2025. Entera Bio Ltd. KIRYAT HADASSAH, MINRAV BUILDING, FIFTH FLOOR, JERUSALEM, ISRAEL, 9112002. OPKO Health, Inc. (the "Reporting Person") 4400 Biscayne Blvd., Miami, FL 33137 State of Delaware Y The information required by Items 4(a) - (c) is set forth in Rows 5 - 11 of the cover page for the Reporting Person and is incorporated herein by reference. The percentage set forth in Row (11) of the cover page for each of the Reporting Persons is based on the 45,420,676 shares of ordinary shares of the Issuer outstanding on March 20, 2025, as set forth in the Issuer's Form 10-K filed with the SEC on March 28, 2025. 8.1% The percentage set forth in Row (11) of the cover page for each of the Reporting Persons is based on the 45,420,676 shares of ordinary shares of the Issuer outstanding on March 20, 2025, as set forth in the Issuer's Form 10-K filed with the SEC on March 28, 2025. 3,685,226 Shares - 3,685,226 - Y N Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. OPKO HEALTH, INC. /s/ Steven D. Rubin 04/02/2025