<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2015-07-01</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001637761</issuerCik>
        <issuerName>SeaSpine Holdings Corp</issuerName>
        <issuerTradingSymbol>SPNE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001646772</rptOwnerCik>
            <rptOwnerName>Baker Brian D.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O SEASPINE HOLDINGS CORPORATION,</rptOwnerStreet1>
            <rptOwnerStreet2>2302 LA MIRADA DRIVE</rptOwnerStreet2>
            <rptOwnerCity>VISTA</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92081</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <footnotes></footnotes>

    <remarks>Vice President, Global Operations

Exhibit 24 - Power of Attorney.</remarks>

    <ownerSignature>
        <signatureName>/s/ Paul Benny, Attorney-in-fact</signatureName>
        <signatureDate>2015-07-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
