Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands	Total	Preferred Stock [Member] Convertible Preferred Stock [Member]	Common Stock [Member] Class A Common Stock [Member]	Common Stock [Member] Class B Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]
Convertible Preferred Stock Beginning Balance (in shares) at Dec. 31, 2023		6,840,620
Beginning Balance at Dec. 31, 2023	$ (101,842)	$ 129,825			$ 209	$ (102,051)
Beginning Balance (in shares) at Dec. 31, 2023			313,747
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Conversion of Convertible Preferred Stock for Class A and B Common Stock in connection with the Merger (in shares)		(6,840,620)	6,154,093	686,527
Conversion of Convertible Preferred Stock for Class A and B Common Stock in connection with the Merger	129,825	$ (129,825)	$ 1		129,824
Issuance of Class A Common Stock in the Concurrent Financing, less issuance costs (in shares)			2,571,736
Issuance of Class A Common Stock in the Concurrent Financing, less issuance costs	54,428				54,428
Issuance of stock (in shares)			3,343,604
Issuance of stock	65,499				65,499
Reverse recapitalization transaction costs of OnKure	(2,085)				(2,085)
Issuance of Class A Common Stock for the conversion of Convertible Promissory Notes (in shares)			267,269
Issuance of Class A Common Stock for the conversion of Convertible Promissory Notes	6,120				6,120
Issuance of Class A common stock for the settlement of restricted stock units (in shares)			7,700
Issuance of Class A Common Stock from the exercise of stock options (in shares)			2,476
Issuance of Class A Common Stock from the exercise of stock options	26				26
Adjustment for fractional shares in the reverse recapitalization			(35)
Stock based compensation expense	4,530				4,530
Net loss	(52,673)					(52,673)
Ending Balance at Dec. 31, 2024	$ 103,828		$ 1		258,551	(154,724)
Ending Balance (in shares) at Dec. 31, 2024			12,660,590	686,527
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of Class A Common Stock from the exercise of stock options (in shares)	0
Conversion of Class B Common Stock to Class A Common Stock (in shares)			686,527	(686,527)
Issuance of Class A Common Stock under the Employee Stock Purchase Plan (in shares)			107,930
Issuance of Class A Common Stock under the Employee Stock Purchase Plan	$ 240				240
Vesting of restricted stock units, net (in shares)			218,518
Stock based compensation expense	11,633				11,633
Net loss	(59,517)					(59,517)
Ending Balance at Dec. 31, 2025	$ 56,184		$ 1		$ 270,424	$ (214,241)
Ending Balance (in shares) at Dec. 31, 2025			13,673,565