X0306 4 2016-01-15 0 0001114220 KERYX BIOPHARMACEUTICALS INC KERX 0001636994 Adams Brian C/O KERYX BIOPHARMACEUTICALS, INC. ONE MARINA PARK DRIVE, 12TH FLOOR BOSTON MA 02210 0 1 0 0 VP and General Counsel Common Stock 2016-01-15 4 S 0 1322 3.30 D 53132 D Sale of a total of 1,322 shares of common stock was made in order to satisfy Mr. Adams' income tax withholding obligation upon the vesting of 3,333 shares of restricted stock on January 14, 2016. Mr. Adams had no discretion with respect to such sale, which was transacted automatically in accordance with the Issuer's corporate policies regarding the vesting of restricted stock. Includes 32,581 shares of restricted stock. /s/ Brian Adams 2016-01-20