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Condensed Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Cash flows from operating activities:    
Net loss $ (52,338,959) $ (54,169,029)
Adjustments to reconcile net loss to cash used in operating activities:    
Non-cash consideration received in licensing agreement transaction 0 (945,366)
Unrealized (gain) loss on equity investments (2,003,073) 454,811
Change in accrued interest income and accretion of discount on marketable securities (2,172,254) (1,211,311)
Stock-based compensation expense 7,285,192 6,556,686
Depreciation and amortization expense 568,282 512,505
Amortization of right-of-use asset 1,028,293 869,100
Change in lease liability (533,946) 936,927
Change in operating assets and liabilities:    
Prepaid expenses and other current assets (1,385,052) 109,292
Accounts payable 1,750,026 (5,174,136)
Accrued expenses 2,020,566 (3,166,606)
Net cash used in operating activities (45,780,925) (55,227,127)
Cash flows from investing activities:    
Purchase of marketable securities (112,443,150) (172,964,441)
Sales/maturities of marketable securities 120,000,000 90,000,000
Purchase of long-term equity investments (10,000,000) (2,500,000)
Issuance of convertible short-term note receivable 0 (1,000,000)
Purchases of property and equipment (40,308) (1,224,379)
Software development and other costs (97,147) (194,397)
Net cash used in investing activities (2,580,605) (87,883,217)
Cash flows from financing activities:    
Proceeds from exercise of options and employee stock purchase plan 535,201 180,658
Proceeds from royalty monetization agreement 30,000,000 0
Net cash provided by financing activities 30,535,201 180,658
Net decrease in cash, cash equivalents and restricted cash (17,826,329) (142,929,686)
Cash, cash equivalents and restricted cash, at beginning of period 46,798,599 189,728,285
Cash, cash equivalents and restricted cash, at end of period 28,972,270 46,798,599
Non-cash investing and financing activities:    
Right-of-use asset in exchange for lease liability 0 15,791,769
Conversion of short-term note receivable to long-term equity investment $ 0 $ 1,000,000