X0306 4 2023-02-23 0 0001636651 Ovid Therapeutics Inc. OVID 0001771761 Perone Thomas Michael C/O OVID THERAPEUTICS INC. 441 NINTH AVENUE NEW YORK NY 10001 0 1 0 0 General Counsel, Secretary Stock Option (Right to Buy) 2.50 2023-02-23 4 A 0 175000 0.00 A 2033-02-22 Common Stock 175000 175000 D 25% of the shares subject to the Stock Option will vest and become exercisable on February 23, 2024 and the remaining shares will vest in 36 equal monthly installments thereafter subject to the Reporting Person's continued services through such date. /s/ Danielle Mann for Thomas M. Perone by PoA 2023-02-27