X0306 4 2021-07-14 0 0001636651 Ovid Therapeutics Inc. OVID 0001704636 Rakhit Amit C/O OVID THERAPEUTICS INC. 1460 BROADWAY, SUITE 15044 NEW YORK NY 10036 0 1 0 0 President and CMO Common Stock 2021-07-14 4 M 0 34017 1.89 A 760840 D Common Stock 2021-07-14 4 S 0 34017 3.71 D 726823 D Stock Option (Right to Buy) 1.89 2021-07-14 4 M 0 34017 0.00 A 2029-02-23 Common Stock 34017 90983 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.70 to $3.745, inclusive. The reporting person undertakes to provide to Ovid Therapeutics Inc, any security holder of Ovid Therapeutics Inc, or staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this Footnote 1 to this Form 4 25% of the Stock Options vested and become exercisable on February 24, 2020 and the remaining shares will vest in 36 equal monthly installments thereafter subject to the Reporting Person's continued services through such date. /s/ Danielle Mann for Amit Rakhit by PoA 2021-07-16