X0306 4 2021-07-09 0 0001636651 Ovid Therapeutics Inc. OVID 0001871782 Poole Robert Michael C/O OVID THERAPEUTICS INC. 1460 BROADWAY, SUITE 15044 NEW YORK NY 10036 1 0 0 0 Stock Option (Right to Buy) 3.94 2021-07-09 4 A 0 30000 0.00 A 2031-07-08 Common Stock 30000 30000 D The option shall vest as follows: 1/36th of the shares subject to the option shall vest every month after July 9, 2021, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2017 Equity Incentive Plan) on each vesting date. /s/ Danielle Mann for Robert Michael Poole by PoA 2021-07-13