X0306 4 2021-06-02 0 0001636651 Ovid Therapeutics Inc. OVID 0001311404 Rona Jeffrey A C/O OVID THERAPEUTICS INC. 1460 BROADWAY, SUITE 15044 NEW YORK NY 10036 0 1 0 0 Chief Business Officer Stock Option (Right to Buy) 4.42 2021-06-02 4 A 0 100000 0.00 A 2031-06-01 Common Stock 100000 100000 D 25% of the shares subject to the Stock Option will vest and become exercisable on June 2, 2022 and the remaining shares will vest in 36 equal monthly installments thereafter subject to the Reporting Person's continued services through such date. /s/ Danielle Mann by PoA for Jeffrey Rona 2021-06-10