X0306 4 2017-09-05 0 0001636651 Ovid Therapeutics Inc. OVID 0001716354 Ward Ana C/O OVID THERAPEUTICS INC. 1460 BROADWAY, SUITE 15044 NEW YORK NY 10036 0 1 0 0 SVP and General Counsel Stock Option Grant (Right to Buy) 8.38 2017-09-05 4 A 0 95000 0.00 A 2027-09-04 Common Stock 95000 95000 D 25% of the shares subject to the Stock Option will vest and become exercisable on September 1, 2018 and the remaining shares will vest in 36 equal monthly installments thereafter subject to the Reporting Person's continued service through each such date. /s/ Laura Berezin, Attorney-in-Fact 2017-09-06