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Condensed Consolidated Statements of Operations - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2026
Sep. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Operating expenses:        
Research and development [1] $ 89,169,000 $ 45,247,000 $ 215,083,000 $ 127,015,000
General and administrative [2] 16,550,000 11,641,000 47,916,000 35,375,000
Gain on sale of in-process research and development asset 0 0 (70,000,000) (10,000,000)
Total operating expenses 105,719,000 56,888,000 192,999,000 152,390,000
Loss from operations (105,719,000) (56,888,000) (192,999,000) (152,390,000)
Other income (expense):        
Interest income 10,625,000 5,379,000 27,673,000 17,746,000
Other (expense) income, net (1,027,000) 40,326,000 (36,000,000) 41,956,000
Total other income (expense) 9,598,000 45,705,000 (8,327,000) 59,702,000
Loss before income tax benefit (96,121,000) (11,183,000) (201,326,000) (92,688,000)
Income tax benefit 0 0 0 15,000
Net loss (96,121,000) (11,183,000) $ (201,326,000) (92,673,000)
Net loss per share, diluted (in dollars per share)     $ (2.04)  
Related Party        
Operating expenses:        
Research and development 100,000 7,000,000.0 $ 3,200,000 9,600,000
General and administrative 300,000 300,000 800,000 800,000
Series A Non Voting Convertible Preferred Stock        
Other income (expense):        
Net loss $ (13,012,000) $ (2,066,000) $ (28,285,000) $ (17,138,000)
Net loss per share, basic (in dollars per share) $ (37.60) $ (5.97) $ (81.74) $ (49.53)
Net loss per share, diluted (in dollars per share) $ (37.60) $ (5.97) $ (81.74) $ (49.53)
Weighted-average common stock outstanding, basic (in shares) 346,045 346,045 346,045 346,045
Weighted-average common stock outstanding, diluted (in shares) 346,045 346,045 346,045 346,045
Series B Non Voting Convertible Preferred Stock        
Other income (expense):        
Net loss $ 0 $ (100,000) $ (868,000) $ (825,000)
Net loss per share, basic (in dollars per share) $ 0 $ (5.97) $ (81.74) $ (49.53)
Net loss per share, diluted (in dollars per share) $ 0 $ (5.97) $ (81.74) $ (49.53)
Weighted-average common stock outstanding, basic (in shares) 0 16,667 10,623 16,667
Weighted-average common stock outstanding, diluted (in shares) 0 16,667 10,623 16,667
Common Stock        
Other income (expense):        
Net loss $ (83,109,000) $ (9,017,000) $ (172,173,000) $ (74,710,000)
Net loss per share, basic (in dollars per share) $ (0.94) $ (0.15) $ (2.04) $ (1.24)
Net loss per share, diluted (in dollars per share) $ (0.94) $ (0.15) $ (2.04) $ (1.24)
Weighted-average common stock outstanding, basic (in shares) 88,410,821 60,414,223 84,255,008 60,338,541
Weighted-average common stock outstanding, diluted (in shares) 88,410,821 60,414,223 84,255,008 60,338,541
[1] Includes related party expenses of $0.1 million and $7.0 million for the three months ended September 30, 2026 and 2025, respectively. Includes related party expenses of $3.2 million and $9.6 million for the nine months ended September 30, 2026 and 2025, respectively.
[2] Includes related party expenses of $0.3 million for the three months ended September 30, 2026 and 2025, and $0.8 million for the nine months ended September 30, 2026 and 2025.