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Stock-based Compensation (Tables)
 9 Months Ended
Sep. 30, 2026
Share-Based Payment Arrangement [Abstract]  
Schedule of Stock Awards Granted Under all Equity Incentive and Inducement Plans
The following table summarizes the Company’s stock awards granted under all equity incentive and inducement plans for each of the periods indicated:
Three Months Ended September 30,Nine Months Ended September 30,
2026202520262025
GrantsWeighted Average Grant Date Fair ValueGrantsWeighted Average Grant Date Fair ValueGrantsWeighted Average Grant Date Fair ValueGrantsWeighted Average Grant Date Fair Value
Stock options80,385$90.34 213,900$15.88 2,849,446$34.81 2,539,617$19.94 
Restricted stock units49,976 $89.63 — — 175,376$47.43 — — 
Schedule of Stock-Based Compensation Expense
Total stock-based compensation expense recognized from the Company’s equity incentive plans, 2018 Plan and 2016 ESPP during the periods presented was as follows (in thousands):
Three Months Ended
September 30,		Nine Months Ended
September 30,
2026202520262025
Research and development
$6,683 $4,248 $18,692 $11,860 
General and administrative7,484 5,318 21,793 15,943 
Total stock-based compensation expense
$14,167 $9,566 $40,485 $27,803 
Schedule of Weighted-Average Assumptions Used in Calculating Fair Value of Awards
The following table summarizes the weighted-average Black-Scholes option pricing model assumptions used to estimate the fair value of stock options granted under the Company's equity incentive plans, and the shares purchased under the 2016 ESPP during the periods presented:
Three Months Ended
September 30,		Nine Months Ended
September 30,
2026202520262025
Stock Options Granted
Expected term (in years)6.086.086.025.98
Expected volatility66%75%73%76%
Risk-free interest rate4.35%3.92%3.89%4.34%
Dividend yield————
2016 ESPP
Expected term (in years)0.500.380.500.44
Expected volatility59%72%63%70%
Risk-free interest rate4.00%4.21%3.69%4.22%
Dividend yield————