Related Party Transactions - Narrative (Details)			3 Months Ended		6 Months Ended
		Nov. 22, 2023 installment $ / shares shares	Jun. 30, 2026 USD ($) seat shares	Jun. 30, 2025 USD ($) shares	Jun. 30, 2026 USD ($) seat shares	Jun. 30, 2025 USD ($) shares	Dec. 31, 2025 USD ($)
Related Party Transaction [Line Items]
Research and development	[1]		$ 65,503,000	$ 40,145,000	$ 125,914,000	$ 81,768,000
Options granted to purchase (in shares) | shares			190,456	427,800	2,769,061	2,325,717
Stock-based compensation expense			$ 13,512,000	$ 9,378,000	$ 26,318,000	$ 18,237,000
Related Party
Related Party Transaction [Line Items]
Research and development			0	0	3,100,000	2,600,000
Total related party accounts payable			0		0		$ 0
Paragon Agreement | Related Party
Related Party Transaction [Line Items]
Amount of related party transaction			$ 100,000	0	$ 100,000	200,000
Appoint Of Board Members
Related Party Transaction [Line Items]
Number of board seats held by related party | seat			1		1
Other Paragon Reimbursable Expenses | Related Party
Related Party Transaction [Line Items]
Research and development			$ 0	0	$ 100,000	100,000
Subsequent to Asset Acquisition | Related Party
Related Party Transaction [Line Items]
Amount of related party transaction			0	0
Consulting Agreement | Related Party
Related Party Transaction [Line Items]
Options granted to purchase (in shares) | shares		477,000
Exercise price (in dollars per share) | $ / shares		$ 10.39
Number of monthly installments | installment		36
Stock-based compensation expense			$ 200,000	$ 200,000	$ 500,000	$ 500,000
Consulting Agreement | Related Party | Share-Based Payment Arrangement, Tranche One
Related Party Transaction [Line Items]
Vesting percentage		25.00%
Vest period grant date (in years)		1 year
Paragon Therapeutics Inc | Maximum | Paragon Agreement | Related Party
Related Party Transaction [Line Items]
Percentage of ownership by noncontrolling owner			5.00%		5.00%
Fairmount Funds Management LLC | Minimum | Paragon Agreement | Related Party
Related Party Transaction [Line Items]
Percentage of ownership by noncontrolling owner			5.00%		5.00%
Percentage of ownership held in third party			5.00%		5.00%

[1] Includes de minimis related party expenses for the three months ended June 30, 2026 and 2025. Includes related party expenses of $3.1 million and $2.6 million for the six months ended June 30, 2026 and 2025, respectively.