Convertible Preferred Stock and Stockholders’ Equity (Details)													1 Months Ended			3 Months Ended		12 Months Ended
	Oct. 15, 2025 USD ($) $ / shares shares	Nov. 29, 2024 shares	Nov. 20, 2024 USD ($) $ / shares shares	May 14, 2024 shares	Apr. 23, 2024 shares	Mar. 20, 2024 USD ($) $ / shares shares	Mar. 18, 2024 shares	Dec. 11, 2023 USD ($) $ / shares shares	Dec. 08, 2023	Jul. 07, 2023 shares	Jun. 26, 2023 USD ($) $ / shares shares	Jun. 22, 2023	Feb. 12, 2026 USD ($) $ / shares shares	Jun. 30, 2023 shares	May 31, 2022 $ / shares	Dec. 31, 2025 USD ($) Vote $ / shares shares	Dec. 31, 2023 $ / shares shares	Dec. 31, 2025 USD ($) Vote $ / shares shares	Dec. 31, 2024 USD ($) $ / shares shares	Dec. 31, 2023 $ / shares shares	Feb. 28, 2025 USD ($)	Sep. 06, 2024 USD ($)	Apr. 25, 2024 shares	Dec. 31, 2022 shares
Class Of Stock [Line Items]
Shares authorized (in shares)																410,000,000		410,000,000
Common stock, authorized (in shares)																400,000,000		400,000,000	400,000,000
Preferred stock, authorized (in shares)																10,000,000		10,000,000
Convertible preferred stock, par value (in dollars per share) | $ / shares																$ 0.0001		$ 0.0001
Common stock, par value (in dollars per share) | $ / shares																$ 0.0001		$ 0.0001	$ 0.0001
Number of votes for common stock holders | Vote																1		1
Common stock dividends declared | $																		$ 0	$ 0
Issuance of Series B non-voting convertible preferred stock in connection with private placement, net of financing costs (in shares)								150,000
Exercise price per warrant (in dollars per share) | $ / shares															$ 0.0025
Maximum ownership percentage of common stock shares for outstanding warrants to be exercised															4.99%
Ownership percentage for outstanding warrants to purchase shares of common stock to be exercised to certain holders															9.99%
Maximum ownership percentage of common stock shares for outstanding warrants to be exercised upon written notice															19.90%
Revised ownership percentage, period to take effect after notice															61 days
Number of warrants outstanding (in shares)																0		0
Parapyre Warrants
Class Of Stock [Line Items]
Warrants to purchase shares (in shares)																	684,407		848,184	684,407
Exercise price per warrant (in dollars per share) | $ / shares																	$ 21.52		$ 23.28	$ 21.52
Number of warrants exercised (in shares)																0		0
Common Stock
Class Of Stock [Line Items]
Conversion of non-voting convertible preferred stock into common stock (in shares)																			10,198,000
Exchange of Series A non-voting convertible preferred stock for common stock (in shares)																			3,640,000
Common Stock | Conversion of Series A Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Conversion of non-voting convertible preferred stock into common stock (in shares)																	25,972,080
Common Stock | Conversion of Series B Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Conversion of non-voting convertible preferred stock into common stock (in shares)				10,198,320															10,198,320
Series B Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Preferred stock, authorized (in shares)																271,625		271,625	271,625
Convertible preferred stock, par value (in dollars per share) | $ / shares																$ 0.0001		$ 0.0001	$ 0.0001
Issuance of Series B non-voting convertible preferred stock in connection with private placement, net of financing costs (in shares)						121,625	271,625	150,000
Conversion basis						40		40	40
Preferred stock, outstanding (in shares)																16,667		16,667	16,667
Preferred stock, not automatically converted, outstanding (in shares)																16,667		16,667
Series B Non-Voting Convertible Preferred Stock | Minimum
Class Of Stock [Line Items]
Beneficial holders owned percentage									0.00%
Series B Non-Voting Convertible Preferred Stock | Maximum
Class Of Stock [Line Items]
Beneficial holders owned percentage									19.90%
Series B Non-Voting Convertible Preferred Stock | Preferred Stock
Class Of Stock [Line Items]
Issuance of Series B non-voting convertible preferred stock in connection with private placement, net of financing costs (in shares)																			122,000	150,000
Conversion of non-voting convertible preferred stock into common stock (in shares)																			(255,000)
Preferred stock, outstanding (in shares)																17,000	0	17,000	17,000	0				0
Series B Non-Voting Convertible Preferred Stock | Preferred Stock | Conversion of Series B Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Conversion of non-voting convertible preferred stock into common stock (in shares)				254,958															254,958
Common Stock
Class Of Stock [Line Items]
Exchange of Series A non-voting convertible preferred stock for common stock (in shares)					3,639,680
Series A Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Preferred stock, authorized (in shares)																1,086,341		1,086,341	1,086,341
Convertible preferred stock, par value (in dollars per share) | $ / shares																$ 0.0001		$ 0.0001	$ 0.0001
Preferred stock issued and outstanding percentage												30.00%
Conversion basis												40
Preferred stock, outstanding (in shares)																346,045	437,037	346,045	346,045	437,037			346,045
Series A Non-Voting Convertible Preferred Stock | Minimum
Class Of Stock [Line Items]
Beneficial holders owned percentage												0.00%
Series A Non-Voting Convertible Preferred Stock | Maximum
Class Of Stock [Line Items]
Beneficial holders owned percentage												19.90%
Series A Non-Voting Convertible Preferred Stock | Common Stock
Class Of Stock [Line Items]
Conversion of non-voting convertible preferred stock into common stock (in shares)																				25,972,000
Series A Non-Voting Convertible Preferred Stock | Preferred Stock
Class Of Stock [Line Items]
Issuance of Series A non-voting convertible preferred stock in connection with the asset acquisition of Spyre and settlement of related forward contract (in shares)										364,887										365,000
Conversion of non-voting convertible preferred stock into common stock (in shares)																				(649,000)
Preferred stock, outstanding (in shares)																346,000	437,000	346,000	346,000	437,000				0
Exchange of Series A non-voting convertible preferred stock for common stock (in shares)																			(91,000)
Series A Non-Voting Convertible Preferred Stock | Preferred Stock | Conversion of Series A Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Conversion of non-voting convertible preferred stock into common stock (in shares)					90,992												649,302
Private Placement
Class Of Stock [Line Items]
Sale of stock (in shares)											721,452			721,452
Public offering price (in dollars per share) | $ / shares											$ 291.08
Aggregate purchase price for stock sold | $								$ 84,600,000			$ 197,300,000
Offering costs | $						$ 11,200,000		$ 5,400,000			$ 12,700,000
Private Placement | Series B Non-Voting Convertible Preferred Stock
Class Of Stock [Line Items]
Public offering price (in dollars per share) | $ / shares						$ 1,480		$ 600
Aggregate purchase price for stock sold | $						$ 168,900,000		$ 169,100,000
Offering costs | $						$ 11,200,000		$ 10,900,000
Issuance of Series B non-voting convertible preferred stock in connection with private placement, net of financing costs (in shares)						121,625	271,625	150,000
Private Placement | Series B Non-Voting Convertible Preferred Stock | Common Stock
Class Of Stock [Line Items]
Sale of stock (in shares)								6,000,000
Public offering price (in dollars per share) | $ / shares								$ 15.00
At-The-Market Offering
Class Of Stock [Line Items]
Sale of stock, authorized amount | $																						$ 500,000,000.0
At-The-Market Offering | Common Stock
Class Of Stock [Line Items]
Sale of stock (in shares)																445,668		445,668	777,432
Public offering price (in dollars per share) | $ / shares																$ 33.772		$ 33.772	$ 26.935
Aggregate purchase price for stock sold | $																$ 14,800,000		$ 14,800,000	$ 20,500,000
Offering costs | $																300,000		300,000	$ 400,000
Sale of stock, authorized amount | $																					$ 500,000,000.0
Sale of stock, aggregate offering price | $																					$ 179,100,000	$ 200,000,000.0
Sale of stock, remaining authorized amount available for sale | $																$ 164,100,000		$ 164,100,000
At-The-Market Offering | Common Stock | Subsequent Event
Class Of Stock [Line Items]
Sale of stock (in shares)													296,396
Public offering price (in dollars per share) | $ / shares													$ 33.566
Aggregate purchase price for stock sold | $													$ 9,700,000
Offering costs | $													200,000
Sale of stock, remaining authorized amount available for sale | $													$ 154,100,000
November 2024 Underwritten Offering | Common Stock
Class Of Stock [Line Items]
Sale of stock (in shares)			8,366,250
Public offering price (in dollars per share) | $ / shares			$ 27.50
Aggregate purchase price for stock sold | $			$ 215,900,000
Offering costs | $			$ 14,200,000
Over-Allotment Option | Common Stock
Class Of Stock [Line Items]
Sale of stock (in shares)	2,229,729	1,091,250
October 2025 Underwritten Offering | Common Stock
Class Of Stock [Line Items]
Sale of stock (in shares)	17,094,594
Public offering price (in dollars per share) | $ / shares	$ 18.50
Aggregate purchase price for stock sold | $	$ 296,400,000
Offering costs | $	$ 19,900,000