Related Party Transactions - Schedule of Expenses related to Related Party which were Settled in Cash (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Related Party Transaction [Line Items]
Research and development	[1]	$ 171,653	$ 162,790	$ 89,504
Related Party
Related Party Transaction [Line Items]
Research and development		10,500	40,100	48,500
Paragon and License Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		10,500	25,500	37,100
Reimbursable costs under the Paragon Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		100	15,300	37,100
License Agreements milestone and sublicensing fees | Related Party
Related Party Transaction [Line Items]
Research and development		$ 10,400	$ 10,200	$ 0

[1] Includes $10.5 million, $40.1 million and $48.5 million in related party expenses for the years ended December 31, 2025, 2024 and 2023, respectively.