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Reimbursable research costs.

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Related Party Transaction, Number Of Board Seats

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Research initiation fees.

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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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The equity interest of noncontrolling shareholders, partners or other equity holders in consolidated entity.

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The cash inflow associated with the amount received from entity's raising of capital via private rather than public placement.

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Amount of transactions with related party during the financial reporting period.

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Amount of noncash expense for share-based payment arrangement.

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Gross number of share options (or share units) granted during the period.

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Related Party Transactions - Narrative (Details)			1 Months Ended	12 Months Ended
Related Party Transactions - Narrative (Details)	Nov. 22, 2023 installment $ / shares shares	Jun. 22, 2023 USD ($)	May 31, 2023 USD ($)	Dec. 31, 2025 USD ($) seat shares	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Mar. 31, 2024
Related Party Transaction [Line Items]
Stock-based compensation				$ 37,614,000	$ 44,833,000	$ 25,675,000
Options granted (in shares) \| shares				2,623,217
Private Placement
Related Party Transaction [Line Items]
Proceeds from issuance of private placement, net				$ 180,000,000.0
Parapyre Option Obligation
Related Party Transaction [Line Items]
Stock-based compensation				0
Related Party
Related Party Transaction [Line Items]
Development cost reduction percentage							50.00%
Stock-based compensation				1,000,000.0	15,600,000	11,500,000
Related Party \| Parapyre Option Obligation
Related Party Transaction [Line Items]
Stock-based compensation				0	14,500,000	11,400,000
Paragon Agreement
Related Party Transaction [Line Items]
Related party expenses incurred prior to asset acquisition		$ 19,000,000.0
Related party expenses unpaid prior to asset acquisition		19,000,000.0
Paragon Agreement \| Related Party
Related Party Transaction [Line Items]
Research initiation fees		3,000,000.0	$ 3,000,000.0
Reimbursable research costs		$ 16,000,000.0
Amount of related party transaction				$ 200,000	31,800,000	39,500,000
Reduction in research and development expense					5,900,000
Common stock, shares outstanding, percentage available to purchase on a diluted basis				1.00%
Appoint of Board Members
Related Party Transaction [Line Items]
Number of board seats held by related party \| seat				2
Paragon Agreement, Subsequent to Asset Acquisition \| Related Party
Related Party Transaction [Line Items]
Amount of related party transaction				$ 100,000	29,800,000	48,500,000
Sale of Stock, December 2023 PIPE \| Related Party
Related Party Transaction [Line Items]
Proceeds from issuance of private placement, net				10,000,000.0
Consulting Agreement \| Related Party
Related Party Transaction [Line Items]
Options granted (in shares) \| shares	477,000
Exercise price (in dollars per share) \| $ / shares	$ 10.39
Number of monthly installments \| installment	48
Stock-based compensation expense				$ 1,000,000.0	$ 1,100,000	$ 100,000
Consulting Agreement \| Related Party \| Share-Based Payment Arrangement, Tranche One
Related Party Transaction [Line Items]
Vesting percentage	25.00%
Awards granted, vesting period	1 year
Paragon Therapeutics Inc \| Maximum \| Paragon Agreement \| Related Party
Related Party Transaction [Line Items]
Percentage of ownership by noncontrolling owner				5.00%
Fairmount Funds Management LLC \| Minimum \| Paragon Agreement \| Related Party
Related Party Transaction [Line Items]
Percentage of ownership by noncontrolling owner				5.00%
Percentage of ownership held in third party				5.00%