Licensing Agreements (Details) - Related Party - USD ($)			12 Months Ended
	Oct. 11, 2024	May 14, 2024	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Reimbursable costs under the Paragon Agreement
Related Party Transaction [Line Items]
Campaign timeline, minimum term			5 years
Royalty step-down percentage			33.00%
Royalty term expiration period			12 years
Termination notice period			60 days
Sublicensing fee			$ 1,900,000	$ 700,000	$ 0
Milestone expense recognized			8,500,000	9,500,000	0
Milestone payments, outstanding and payable			0	0
Milestone payments			8,500,000	9,500,000	0
Sublicensing fee payments			2,400,000	200,000	$ 0
SPY001 License Agreement
Related Party Transaction [Line Items]
Milestone payments		$ 3,000,000.0
SPY002 License Agreement
Related Party Transaction [Line Items]
Milestone payments		3,000,000.0
SPY003 License Agreement
Related Party Transaction [Line Items]
Milestone payments	$ 3,000,000.0
License Agreements milestone and sublicensing fees
Related Party Transaction [Line Items]
Sublicensing fees, outstanding and payable			0	$ 500,000
Maximum | SPY001 License Agreement
Related Party Transaction [Line Items]
Contingent obligation based on milestones		22,000,000.0
Maximum | SPY002 License Agreement
Related Party Transaction [Line Items]
Contingent obligation based on milestones		$ 22,000,000.0
Sublicensing fee			$ 20,000,000.0
Maximum | SPY003 License Agreement
Related Party Transaction [Line Items]
Contingent obligation based on milestones	$ 22,000,000.0