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Condensed Consolidated Statements of Cash Flows
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2024
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
CASH FLOWS FROM OPERATING ACTIVITIES      
Net loss $ (38,837) $ (81,490) $ (82,694)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation 8,700 18,237 22,517
Change in fair value of CVR liability   (1,800) 930
Gain on sale of in-process research and development asset 0 (10,000) 0
Net accretion of discount on marketable securities   (4,655) (5,984)
Interest proceeds from maturities of zero coupon U.S. Treasury Bills   1,760 124
Changes in operating assets and liabilities:      
Accounts payable   3,046 2,335
Accrued and other liabilities   (8,299) (7,623)
Related party accounts payable   (572) (12,906)
Prepaid expenses and other assets   (3,784) (7,489)
Net cash used in operating activities   (87,557) (90,790)
CASH FLOWS FROM INVESTING ACTIVITIES      
Proceeds from maturities and sales of marketable securities   178,249 105,626
Purchases of marketable securities   (106,312) (331,107)
Proceeds from sale of in-process research and development asset   7,000 0
Net cash provided by (used in) investing activities   78,937 (225,481)
CASH FLOWS FROM FINANCING ACTIVITIES      
Proceeds from issuance of Series B non-voting convertible preferred stock in connection with private placement, net of placement and other offering costs   0 169,070
Payments related to CVR   0 (1,430)
Payment of deferred offering costs in connection with shelf registration   (93) 0
Proceeds from employee stock option exercises and employee stock plan purchases   1,066 4,885
Cash settlement of employee stock option award   (117) 0
Net cash provided by financing activities   856 172,525
Effect of exchange rate on cash, cash equivalents, and restricted cash   0 (4)
NET DECREASE IN CASH, CASH EQUIVALENTS, AND RESTRICTED CASH   (7,764) (143,750)
CASH, CASH EQUIVALENTS, AND RESTRICTED CASH      
Beginning of period   89,423 189,215
End of period 45,465 81,659 45,465
Supplemental Disclosure of Non-Cash Financing Information:      
Exchange of Series A non-voting convertible preferred stock for common stock   0 38,502
Conversion of Series B non-voting convertible preferred stock into common stock   0 244,010
Unpaid amounts related to issuance of Series B non-voting convertible preferred stock in connection with private placement   0 220
Reconciliation of Cash, Cash Equivalents, and Restricted Cash Reported in the Statement of Financial Position:      
Cash and cash equivalents 45,144 81,659 45,144
Restricted cash 321 0 321
Total cash, cash equivalents, and restricted cash shown in the statement of cash flows $ 45,465 $ 81,659 $ 45,465