Segment Reporting - Schedule of Significant Expenses Provided to the CODM on a Regular Basis (Details) - USD ($) $ in Thousands		3 Months Ended				6 Months Ended
		Jun. 30, 2025	Mar. 31, 2025	Jun. 30, 2024	Mar. 31, 2024	Jun. 30, 2025	Jun. 30, 2024
Segment, Reconciliation of Other Items from Segments to Consolidated [Line Items]
Stock-based compensation				$ 8,700		$ 18,237	$ 22,517
Net loss		$ 36,717	$ 44,773	38,837	$ 43,857	81,490	82,694
Reconciliation of net loss
Adjustments and reconciling items		36,717	44,773	38,837	43,857	81,490	82,694
Net loss		36,717	$ 44,773	38,837	$ 43,857	81,490	82,694
Research and development	[1]	40,145		32,636		81,768	67,564
Gain recognized within operating expenses		10,000		0		10,000	0
Related Party
Segment, Reconciliation of Other Items from Segments to Consolidated [Line Items]
Stock-based compensation		200		1,700		500	7,400
Related Party | Paragon and License Agreement
Reconciliation of net loss
Research and development		0		7,900		2,600	19,600
Reportable Segment
Segment, Reconciliation of Other Items from Segments to Consolidated [Line Items]
Net loss		36,717		38,837		81,490	82,694
Reconciliation of net loss
Adjustments and reconciling items		36,717		38,837		81,490	82,694
Net loss		36,717		38,837		81,490	82,694
Operating Segments | Reportable Segment
Segment, Reconciliation of Other Items from Segments to Consolidated [Line Items]
Compensation		8,120		4,881		15,111	9,055
Stock-based compensation		9,378		8,682		18,237	22,517
Research and development, excluding compensation and share-based compensation		30,749		26,808		64,300	52,910
Other segment items		(11,530)		(1,534)		(16,158)	(1,788)
Net loss		36,717		38,837		81,490	82,694
Reconciliation of net loss
Adjustments and reconciling items		36,717		38,837		81,490	82,694
Net loss		36,717		38,837		81,490	82,694
Adjustments and reconciling items | Reportable Segment
Segment, Reconciliation of Other Items from Segments to Consolidated [Line Items]
Net loss		0		0		0	0
Reconciliation of net loss
Adjustments and reconciling items		0		0		0	0
Net loss		$ 0		$ 0		$ 0	$ 0

[1] Includes de minimis and $2.6 million in related party expenses for the three and six months ended June 30, 2025, respectively, and $9.4 million and $26.5 million related party expenses for the three and six months ended June 30, 2024, respectively.