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Related Party Transactions - Narrative (Details)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Nov. 22, 2023
$ / shares
shares
Jun. 30, 2025
USD ($)
seat
shares
Jun. 30, 2024
USD ($)
shares
Jun. 30, 2025
USD ($)
seat
shares
Jun. 30, 2024
USD ($)
shares
Apr. 01, 2024
Mar. 31, 2024
Related Party Transaction [Line Items]              
Stock-based compensation expense     $ 8,700 $ 18,237 $ 22,517    
Options granted to purchase (in shares) | shares   427,800 387,695 2,325,717 1,432,353    
Stock-based compensation expense   $ 9,378 $ 8,682 $ 18,237 $ 22,517    
Parapyre Option Obligation              
Related Party Transaction [Line Items]              
Stock-based compensation expense     1,500   6,900    
Related Party              
Related Party Transaction [Line Items]              
Development cost reduction (as percent)           50.00%  
Development cost reimbursement (as percent)             50.00%
Stock-based compensation expense   200 1,700 500 7,400    
Paragon Agreement | Related Party              
Related Party Transaction [Line Items]              
Amount of related party transaction   $ 0 11,300 $ 200 29,500    
Receivable recognized     5,900   5,900    
Common stock, shares outstanding, percentage available to purchase on a diluted basis   1.00%   1.00%      
Appoint Of Board Members              
Related Party Transaction [Line Items]              
Number of board seats held by related party | seat   2   2      
Subsequent to Asset Acquisition | Related Party              
Related Party Transaction [Line Items]              
Amount of related party transaction   $ 0 9,700 $ 100 26,800    
Consulting Agreement | Related Party              
Related Party Transaction [Line Items]              
Options granted to purchase (in shares) | shares 477,000            
Exercise price (in dollars per share) | $ / shares $ 10.39            
Vest period grant date (in years) 36 months            
Stock-based compensation expense   $ 200 $ 500 $ 200 $ 500    
Consulting Agreement | Related Party | Share-Based Payment Arrangement, Tranche One              
Related Party Transaction [Line Items]              
Vesting percentage 25.00%            
Vest period grant date (in years) 1 year            
Paragon Therapeutics Inc | Maximum | Paragon Agreement | Related Party              
Related Party Transaction [Line Items]              
Percentage of ownership by noncontrolling owner   5.00%   5.00%      
Fairmount Funds Management LLC | Minimum | Paragon Agreement | Related Party              
Related Party Transaction [Line Items]              
Percentage of ownership by noncontrolling owner   5.00%   5.00%      
Percentage of ownership held in third party   5.00%   5.00%