Related Party Transactions - Expenses related to Related Party which were Settled in Cash (Details) - USD ($) $ in Thousands		3 Months Ended
		Mar. 31, 2025	Mar. 31, 2024
Related Party Transaction [Line Items]
Research and development	[1]	$ 41,623	$ 34,928
Paragon and License Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		2,500	11,700
Paragon Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		0	11,700
License Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		$ 2,500	$ 0

[1] Includes $2.5 million and $17.1 million in related party expenses for the three months ended March 31, 2025 and 2024, respectively.