Related Party Transactions - Expenses related to Related Party which were Settled in Cash (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Related Party Transaction [Line Items]
Research and development	[1]	$ 162,790	$ 89,504	$ 58,579
Paragon and License Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		25,500	37,100	0
Paragon Agreement | Related Party
Related Party Transaction [Line Items]
Research and development		15,300	37,100	0
Paragon Agreement, License Milestone Payments | Related Party
Related Party Transaction [Line Items]
Research and development		$ 10,200	$ 0	$ 0

[1] Includes $41.2 million and $48.5 million in related party expenses for the years ended December 31, 2024 and December 31, 2023, respectively, and no related party expenses for the year ended December 31, 2022.