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Related Party Transactions - Narrative (Details) $ / shares in Units, $ in Thousands					1 Months Ended	12 Months Ended
	Dec. 14, 2023 USD ($)	Nov. 22, 2023 installment $ / shares shares	Jul. 12, 2023 USD ($)	Jun. 22, 2023 USD ($)	May 31, 2023 USD ($)	Dec. 31, 2023 USD ($) seat shares	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Related Party Transaction [Line Items]
Stock compensation expense						$ 25,675	$ 7,111	$ 8,038
Related party accounts payable and other current liabilities						16,584	0
Proceeds from issuance of private placement						$ 84,555	0	0
Granted (in shares) \| shares						8,776,245
Related Party
Related Party Transaction [Line Items]
Related party accounts payable and other current liabilities						$ 16,600	0
Appoint Of Board Members
Related Party Transaction [Line Items]
Number of board seats held by related party \| seat						2
Paragon Agreement
Related Party Transaction [Line Items]
Related party expenses incurred prior to asset acquisition				$ 19,000
Related party expenses unpaid prior to asset acquisition				19,000
Paragon Agreement \| Related Party
Related Party Transaction [Line Items]
Research initiation fees				3,000	$ 3,000
Reimbursable research costs				$ 16,000
Stock compensation expense						$ 11,400
Stock Compensation And Research And Development Expense
Related Party Transaction [Line Items]
Related party transaction amount						48,500
Reimbursable Costs Under Paragon Agreement \| Related Party
Related Party Transaction [Line Items]
Related party accounts payable and other current liabilities						16,600	0
Milestone Payments
Related Party Transaction [Line Items]
Related party transaction amount						39,500
SPY001 License Agreement \| Related Party
Related Party Transaction [Line Items]
Nomination fee			$ 1,500
Milestone payments			2,500
SPY002 License Agreement \| Related Party
Related Party Transaction [Line Items]
Nomination fee	$ 1,500
Milestone payments	2,500
Sale Of Stock, December 2023 PIPE \| Related Party
Related Party Transaction [Line Items]
Proceeds from issuance of private placement						10,000
Consulting Agreement \| Related Party
Related Party Transaction [Line Items]
Granted (in shares) \| shares		477,000
Exercise price (in dollars per share) \| $ / shares		$ 10.39
Number of monthly installments \| installment		48
Stock-based compensation expense						$ 100	$ 0	$ 0
Consulting Agreement \| Related Party \| Share-Based Payment Arrangement, Tranche One
Related Party Transaction [Line Items]
Vesting percentage		25.00%
Awards granted, vesting period		1 year
Paragon Therapeutics Inc \| Ownership Interest \| Maximum \| Related Party
Related Party Transaction [Line Items]
Percentage of ownership by noncontrolling owner						5.00%
Paragon Therapeutics Inc \| SPY001 License Agreement \| Maximum \| Related Party
Related Party Transaction [Line Items]
Contingent obligation based on milestones			$ 22,000
Paragon Therapeutics Inc \| SPY002 License Agreement \| Maximum \| Related Party
Related Party Transaction [Line Items]
Contingent obligation based on milestones	$ 22,000
Fairmount Funds Management LLC \| Ownership Interest \| Minimum \| Related Party
Related Party Transaction [Line Items]
Percentage of ownership by noncontrolling owner						5.00%
Percentage of ownership held in third party						5.00%