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Stock-Based Compensation - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Oct. 31, 2018
Jun. 30, 2018
Feb. 28, 2018
Apr. 30, 2016
Mar. 31, 2015
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Jan. 01, 2021
Jan. 01, 2020
Jan. 01, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Outstanding option awards and restricted unit awards           6,607,587,000 5,357,844,000        
Tax benefits recognized           $ 0 $ 0 $ 0      
Expected dividend yield           0.00% 0.00% 0.00%      
Employees and Non-Employees                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Expense recognized for unvested employee and non-employee awards           $ 0 $ 0 $ 0      
Stock Options                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Weighted-average grant date fair value           $ 4.96 $ 4.68 $ 8.09      
Intrinsic value of options exercised           $ 700,000 $ 400,000 $ 1,000,000.0      
Unrecognized stock-based compensation expense for options           $ 15,100,000          
Weighted average period over which unrecognized compensation is expected to be recognized           2 years 7 months 6 days          
Stock Options | Non-Employees                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Stock option issued           0 0 0      
Stock option vested           0 1,663 0      
Restricted Common Stock                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Shares, granted to employees           0 228,200 0      
Unrecognized stock-based compensation expense           $ 1,600,000          
Restricted Common Stock | Non-Employees                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Shares, granted to employees           0 0 0      
2015 Equity Incentive Plan                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Grantees with more than five years vesting term, percent         10.00%            
Maximum vesting term for more than ten percent grantees         5 years            
Number of common stock to option outstanding           136,560          
Number of common stock available for issuance       509,869              
2015 Equity Incentive Plan | Minimum                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Percentage of market value of common stock         100.00%            
2015 Equity Incentive Plan | Maximum | Stock option                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Awards granted, expiration period         10 years            
2016 Equity Incentive Plan                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Initial reserves of common stock       1,100,000              
Increase in number of shares of common stock reserved for issuance 1,759,602                    
Share based compensation plan expiration date Aug. 07, 2028                    
Annual percentage of additional shares           4.00%          
Additional number of shares available for issuance                 1,918,363 1,163,377 965,603
Total number of common stock reserved for issuance           8,802,022          
Outstanding option awards and restricted unit awards           6,317,069          
2018 Equity Inducement Plan                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Initial reserves of common stock     1,100,000                
Total number of common stock reserved for issuance           1,100,000          
Outstanding option awards and restricted unit awards           343,958          
2018 Plan, 2016 Plan and 2015 Plan                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Awards granted, expiration period     10 years                
2018 Plan, 2016 Plan and 2015 Plan | Four Year Vesting                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Awards granted, vesting period     4 years                
2018 Plan, 2016 Plan and 2015 Plan | Maximum                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Awards granted, vesting period     4 years                
2016 Employee Stock Purchase Plan                      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                      
Additional number of shares available for issuance                 479,590 290,844 241,400
Total number of common stock reserved for issuance       165,000   874,923          
Percentage of discount through payroll deductions to eligible employees to purchase common stock       15.00%              
Percentage of fair market value of common stock       85.00%              
Maximum number of shares permitted for per employee       2,000              
Maximum purchase value per employee under employee stock purchase plan       $ 25,000              
Employee stock purchase plan termination period       10 years              
Additional annual percentage increase of common stock   1.00%                  
Expected dividend yield           0.00% 0.00% 0.00%