Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenue:
Total revenue	$ 18,739	$ 0	$ 0
Operating expenses:
Research and development	57,069	59,638	64,600
General and administrative	27,319	21,843	15,734
Total operating expenses	84,388	81,481	80,334
Loss from operations	(65,649)	(81,481)	(80,334)
Other income (expense):
Interest income	111	593	2,143
Other expense, net	(122)	(5)	(63)
Total other income (expense)	(11)	588	2,080
Loss before income tax expense	(65,660)	(80,893)	(78,254)
Income tax expense	(141)	0	0
Net loss	$ (65,801)	$ (80,893)	$ (78,254)
Net loss per share, basic and diluted	$ (1.00)	$ (1.52)	$ (2.45)
Weighted-average common shares outstanding, basic and diluted	65,744,611	53,371,730	31,949,633
License [Member]
Revenue:
Total revenue	$ 12,000	$ 0	$ 0
Development Fee [Member]
Revenue:
Total revenue	$ 6,739	$ 0	$ 0