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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (18,728) $ (17,167)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 154 100
Purchase net discount on marketable securities 19 243
Net accretion of discount on marketable securities (48) (275)
Stock-based compensation 1,348 1,081
Non-cash operating lease expense 152 69
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (2,696) (928)
Accounts payable 262 2,289
Operating lease liabilities (92) (114)
Accrued and other liabilities (2,065) (1,105)
Net cash used in operating activities (21,694) (15,807)
CASH FLOWS FROM INVESTING ACTIVITIES    
Purchases of property and equipment (1,389) (118)
Purchases of marketable securities (4,000) (19,750)
Proceeds from maturities of marketable securities 20,142 33,804
Net cash provided by investing activities 14,753 13,936
CASH FLOWS FROM FINANCING ACTIVITIES    
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of offering costs   64,662
Proceeds from employee stock plan purchases and stock option exercises 289 399
Principal payments on finance lease obligation (7) (6)
Net cash provided by financing activities 282 65,055
NET (DECREASE) INCREASE IN CASH, CASH EQUIVALENTS, AND RESTRICTED CASH (6,659) 63,184
CASH, CASH EQUIVALENTS, AND RESTRICTED CASH    
Beginning of period 20,753 22,461
End of period 14,094 85,645
Supplemental Disclosure of Non-Cash Investing and Financing Information:    
Leased assets obtained in exchange for lease obligations 137 $ 776
Unpaid amounts related to purchase of property and equipment $ 1,057